Left ventricular assist devices (LVADs) are implanted for patients with advanced heart failure. LVADs can be used as a temporary solution for patients eligible and awaiting heart transplantation (Bridge-to-Transplant) or as a permanent treatment (Destination Therapy). Since the LVAD only treats the left side of the heart, a possible limitation with LVAD use can be the early or late onset of right ventricular insufficiency. Multiple factors may affect this. While an LVAD improves cardiac output, the decrease in left ventricular pressure can shift the wall between the ventricles (interventricular septum) to the left, leading to enlargement of the right ventricle and possibly an increase leak of the tricuspid valve that is tethered to the inner walls of the right ventricle. In most patients, right ventricular failure does not occur because the lowering of the left heart pressures leads to a lower pressure that the right ventricle has to pump against in the pulmonary artery.